CAS No 4691-65-0 Top Quality 99% Nucleotide
Product name: Inosine 5'-Monophosphate Disodium Salt
Specification: 97% Test method: HPLC
Appearance: White or off white crystalline powder
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Inosine-5'-monophosphate is a substrate of IMP dehydrogenase. Inosine-5'-monophosphate dehydrogenase (IMPDH) is an enzyme responsible for the biosynthesis of guanine nucleotides. IMPDH inhibitors have been approved for the prevention of organ transplant rejection.
This is a rate-limiting step in the generation of guanosine monophosphate, which is important for DNA, RNA, and glycoprotein synthesis. Inhibitors of IMPDH, including ribavirin and mycophenolate mofetil, have potential applications as antiviral and anti-cancer drugs.
IMP is also involved in potentiating the umami taste sensation.
Heavy metal: ≤10mg
Light transmittance (5% solution): ≥95.0%
Properties: white or off-white crystalline powder. Odorless, special umami, slightly hygroscopic, but not deliquescent, soluble in water, insoluble in ethanol, ether.
Cognitive Function and Brain Health
An animal study found that Inosine-5'-monophosphate (IMP) and guanosine monophosphate (GMP) could elicit an umami taste and synergistically enhance the umami taste of monosodium glutamate (MSG). It was found that well-trained rats could detect both nucleotides at nanomolar concentrations, but they did not respond to either nucleotide
in two-bottle preference tests at concentrations less than 0.5 mM. Moreover, discrimination experiments showed that the tastes of tested nucleotides could not be discriminated, but both IMP and GMP could be discriminated from MSG
It goes well with fish oil (Specifically DHA, for cognition) and choline or other cholinergic (Cognition).
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