Inosine 5'-Monophosphate Disodium Salt

Inosine 5'-Monophosphate Disodium Salt

Product name: Inosine 5'-Monophosphate Disodium Salt
CAS: 20813-76-7
Specification: 97%                             Test method: HPLC
Appearance: White or off white crystalline powder

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Product Details

Summary

Inosine-5'-monophosphate is a substrate of IMP dehydrogenase. Inosine-5'-monophosphate dehydrogenase (IMPDH) is an enzyme responsible for the biosynthesis of guanine nucleotides. IMPDH inhibitors have been approved for the prevention of organ transplant rejection.

This is a rate-limiting step in the generation of guanosine monophosphate, which is important for DNA, RNA, and glycoprotein synthesis. Inhibitors of IMPDH, including ribavirin and mycophenolate mofetil, have potential applications as antiviral and anti-cancer drugs.


IMP is also involved in potentiating the umami taste sensation.

CAS:4578-31-8
MDL:MFCD00151004
MF:C10H12N5O7P.2Na.6H2O
MW:499.28


Purity: ≥99.0%

Heavy metal: ≤10mg

Light transmittance (5% solution): ≥95.0%

Properties: white or off-white crystalline powder. Odorless, special umami, slightly hygroscopic, but not deliquescent, soluble in water, insoluble in ethanol, ether.


Function

Cognitive Function and Brain Health


Research

The Cell Membrane

An animal study found that Inosine-5'-monophosphate (IMP) and guanosine monophosphate (GMP) could elicit an umami taste and synergistically enhance the umami taste of monosodium glutamate (MSG). It was found that well-trained rats could detect both nucleotides at nanomolar concentrations, but they did not respond to either nucleotide

in two-bottle preference tests at concentrations less than 0.5 mM. Moreover, discrimination experiments showed that the tastes of tested nucleotides could not be discriminated, but both IMP and GMP could be discriminated from MSG


Notice

It goes well with fish oil (Specifically DHA, for cognition) and choline or other cholinergic (Cognition).

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