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What Is Fisetin?
- Feb 22, 2021 -

Fisetin is a flavonol, a yellow plant pigment that belongs to the flavonoid group of polyphenols. It gives color to many different fruits and vegetables.

Compared to now-famous plant antioxidants like resveratrol and quercetin, fisetin was unfairly ignored for far too long. It wasn’t until recent years that researchers became increasingly interested in its medicinal potential.

Science teams are currently exploring its ability to slow the aging process and extend lifespan – its so-called “senolytic” effects. What’s more, fisetin has powerful anti-inflammatory, antioxidant, and immune-supporting properties.



May protect the brain and improve memory

Might delay aging

Helps control blood sugar

May have anticancer properties

Protects the liver and heart


Clinical trials are lacking

Poorly absorbed

Possible interactions with blood thinners

Unknown safety in humans

Food Sources

Many different fruits and vegetables contain fisetin. Food sources with the highest concentration of fisetin include (expressed as ~micrograms of fisetin per gram of freeze-dried food):




Lotus root




It’s also found in mangoes and cucumbers in lower amounts. The listed fisetin levels were measured in freeze-dried foods. Levels may vary in fresh fruits and vegetables and depend on the conditions they’re grown in.

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