When NMN powder enters the body, the substance that really exerts anti-aging effects is NAD+. As we grow older, the level of NAD+ in the body will continue to decrease, and the body will experience degenerative symptoms, such as muscle degeneration, mental decline, deepening of pigmentation, and hair loss, which is traditionally called "Aging".
Four types of precursor substances supplementing NAD+:
Niacin (NA): Through Preiss-Handler to become NAD+.
Side effects: a. General adverse reactions include: feeling warm, redness of the skin, especially on the face and neck, headache, and other vasodilation reactions.
b. High-dose medication can cause diarrhea, dizziness, fatigue, dry skin, itching, dry eyes, nausea, vomiting, stomach pain, hyperglycemia, hyper uric acid, arrhythmia, liver toxicity.
c. After generally taking niacin for 2 weeks, vasodilation and gastrointestinal discomfort can be gradually adapted. Gradually increasing the dosage can avoid the above reactions. If there is severe skin flushing, itching, or gastrointestinal discomfort, the dose should be reduced.
Tryptophan: Through de novo biosynthesis pathway, enter the Preiss-Handler pathway to become NAD+.
Side effects: Adults take 100~500mg daily
NAM: By salvage synthetic pathway to NAD+.
Side effects: Not suitable for intramuscular injection. Individual patients have dizziness, nausea, upper abdominal discomfort, loss of appetite, skin flushing, fever, and itching. Overdose during pregnancy may cause teratogenicity.
NMN/NR: By salvage synthetic pathway to NAD+.
Side effects: No adverse reactions have been found
Based on the above, NMN has defeated many competitors and has become the most direct and fastest preferred way to supplement NAD+.
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