Magnolia Bark Extract

Brief Introduction:

Magnolia Officinalis is a plant from the Magnolia species of plants which share a set of similar compounds. Two of them, known as Honokiol and Magnolol, are seen as active ingredients.

Magnolia plants tend to be significantly cancer-protective and show protective effects on the liver and the brain via fighting inflammation and oxidation. They have also been linked to anti-depressant and anxiety-reducing effects.

One of the compounds, Honokiol, is currently in trials for usage as an adjunct treatment for cancer therapy.

And the bark of Magnolia Officinalis is the main active ingredient.

Primary Function:

Mood

Stress relief

Goes Well With:

Ginger (ginger enhances the antidepressive effects of Magnolia Officinalis)

Pinellia ternata (synergistically antidepressive)

Note:

The dosage of Magnolia Officinalis to take varies on goal. For those related to GABA (including anxiety, sedation, stress, and epilepsy) an oral dose of 0.2mg/kg in mice appears effective and suggests very lose doses (5-10 mg) are effective in humans.

For those goals related to learning or depression, higher doses may be required. This usually means 15-30mg/kg in rats and suggests a human dose of:

160-330 mg for a 150lb person

220-440 mg for a 200lb person

270-550 mg for a 250lb person

The above doses refer to the total neolignans (usually magnolol plus honokiol), which are usually at 1-10% of a basic bark extract unless otherwise concentrated.

Also Known As:

Saiboku-to, Magnolia Bark Extract, Honokiol, Magnolol